| 2023-02-17 20:00:00February 17, 2023 | Leigh Leopards vs Salford Red Devils, Betfred Super League | 10 - 20 | Super League | Leigh Sports Village Stadium |
| 2023-02-25 18:00:00February 25, 2023 | Catalans Dragons vs Leigh Leopards, Betfred Super League | 14 - 6 | Super League | Stade Gilbert Brutus |
| 2023-03-03 20:00:00March 3, 2023 | Hull KR vs Leigh Leopards, Betfred Super League | 25 - 30 | Super League | Sewell Group Craven Park |
| 2023-03-10 20:00:00March 10, 2023 | Leigh Leopards vs St Helens, Betfred Super League | 20 - 12 | Super League | Leigh Sports Village Stadium |
| 2023-03-17 20:00:00March 17, 2023 | Warrington Wolves vs Leigh Leopards, Betfred Super League | 38 - 20 | Super League | Halliwell Jones Stadium |
| 2023-03-25 15:00:00March 25, 2023 | Hull FC vs Leigh Leopards, Betfred Super League | 16 - 24 | Super League | MKM Stadium |
| 2023-03-30 20:00:00March 30, 2023 | Leigh Leopards vs Wigan Warriors, Betfred Super League | 6 - 34 | Super League | Leigh Sports Village Stadium |
| 2023-04-08 14:30:00April 8, 2023 | Leigh Leopards vs Salford Red Devils, Betfred Super League | 20 - 22 | Super League | Leigh Sports Village Stadium |
| 2023-04-16 15:00:00April 16, 2023 | Wakefield Trinity vs Leigh Leopards, Betfred Super League | 0 - 32 | Super League | The Be Well Support Stadium |
| 2023-04-21 20:00:00April 21, 2023 | Leigh Leopards vs Leeds Rhinos, Betfred Super League | 20 - 6 | Super League | Leigh Sports Village Stadium |
| 2023-05-05 20:00:00May 5, 2023 | Leigh Leopards vs Castleford Tigers, Betfred Super League | 30 - 6 | Super League | Leigh Sports Village Stadium |
| 2023-05-12 19:45:00May 12, 2023 | Huddersfield Giants vs Leigh Leopards, Betfred Super League | 4 - 30 | Super League | John Smith's Stadium |
| 2023-05-19 19:45:00May 19, 2023 | Wakefield Trinity vs Leigh Leopards, Betfred Challenge Cup | 12 - 40 | Challenge Cup | The Be Well Support Stadium |
| 2023-05-26 20:00:00May 26, 2023 | Leigh Leopards vs Warrington Wolves, Betfred Super League | 30 - 12 | Super League | Leigh Sports Village Stadium |
| 2023-06-04 12:00:00June 4, 2023 | Wakefield Trinity vs Leigh Leopards, Betfred Super League | 4 - 30 | Super League | St James' Park |
| 2023-06-09 20:00:00June 9, 2023 | Leigh Leopards vs Hull FC, Betfred Super League | 28 - 16 | Super League | Leigh Sports Village Stadium |
| 2023-06-18 17:00:00June 18, 2023 | York RLFC vs Leigh Leopards, Betfred Challenge Cup | 14 - 34 | Challenge Cup | LNER Community Stadium |
| 2023-06-24 19:00:00June 24, 2023 | Catalans Dragons vs Leigh Leopards, Betfred Super League | 38 - 30 | Super League | Stade Gilbert Brutus |
| 2023-06-30 20:00:00June 30, 2023 | Leigh Leopards vs Hull KR, Betfred Super League | 34 - 4 | Super League | Leigh Sports Village Stadium |
| 2023-07-07 20:00:00July 7, 2023 | Castleford Tigers vs Leigh Leopards, Betfred Super League | 16 - 34 | Super League | The Mend-A-Hose Jungle |
| 2023-07-16 15:00:00July 16, 2023 | Salford Red Devils vs Leigh Leopards, Betfred Super League | 22 - 24 | Super League | Salford Stadium |
| 2023-07-22 14:30:00July 22, 2023 | Leigh Leopards vs St Helens, Betfred Challenge Cup | 12 - 10 | Challenge Cup | Halliwell Jones Stadium |
| 2023-07-29 13:00:00July 29, 2023 | Wigan Warriors vs Leigh Leopards, Betfred Super League | 44 - 18 | Super League | DW Stadium |
| 2023-08-06 15:00:00August 6, 2023 | Leeds Rhinos vs Leigh Leopards, Betfred Super League | 6 - 13 | Super League | Headingley Stadium |
| 2023-08-12 15:00:00August 12, 2023 | Hull KR vs Leigh Leopards, Betfred Challenge Cup | 16 - 17 | Challenge Cup | Wembley Stadium |
| 2023-08-19 15:00:00August 19, 2023 | Leigh Leopards vs Catalans Dragons, Betfred Super League | 14 - 30 | Super League | Leigh Sports Village Stadium |
| 2023-08-25 20:00:00August 25, 2023 | Hull KR vs Leigh Leopards, Betfred Super League | 52 - 10 | Super League | Sewell Group Craven Park |
| 2023-09-03 15:00:00September 3, 2023 | Leigh Leopards vs Huddersfield Giants, Betfred Super League | 34 - 16 | Super League | Leigh Sports Village Stadium |
| 2023-09-08 20:00:00September 8, 2023 | St Helens vs Leigh Leopards, Betfred Super League | 22 - 12 | Super League | The BrewDog Stadium |
| 2023-09-15 20:00:00September 15, 2023 | Leigh Leopards vs Wakefield Trinity, Betfred Super League | 20 - 19 | Super League | Leigh Sports Village Stadium |
| 2023-09-22 20:00:00September 22, 2023 | Leigh Leopards vs Wigan Warriors, Betfred Super League | 6 - 10 | Super League | Leigh Sports Village Stadium |
| 2023-09-29 20:00:00September 29, 2023 | Hull KR vs Leigh Leopards, Betfred Super League | 20 - 6 | Super League | Sewell Group Craven Park |
